What is the primary mechanism of action of the adjunctive medication pramlintide?

Pramlintide is a synthetic analog of amylin, a hormone that is co-secreted with insulin from the beta cells of the pancreas. It primarily functions by suppressing glucagon secretion, which helps to reduce glucose output from the liver. Additionally, pramlintide slows gastric emptying, leading to a more gradual absorption of nutrients and glucose into the bloodstream, which can help control postprandial blood glucose levels. Furthermore, it increases feelings of satiety, which can assist with weight management in patients with diabetes. This combination of effects makes pramlintide a valuable adjunct in the management of diabetes, particularly in conjunction with insulin therapies.

The other options describe mechanisms not associated with pramlintide. While they highlight important pathways in glucose regulation and diabetes management, they do not apply directly to pramlintide's specific actions. Thus, the correct answer accurately reflects pramlintide's primary mechanisms of action.