What is the primary action of Metformin in the management of type 2 diabetes?

What is the primary action of Metformin in the management of type 2 diabetes?

• A. It increases hepatic glucose production
• B. It improves insulin sensitivity and decreases hepatic glucose production
• C. It directly increases blood sugar levels
• D. It works by stimulating insulin release from the pancreas

Answer: (B)

Metformin's primary action in managing type 2 diabetes is to improve insulin sensitivity and decrease hepatic glucose production. This dual mechanism is crucial for controlling blood glucose levels in patients with type 2 diabetes. By enhancing insulin sensitivity, Metformin allows the body's cells to use insulin more effectively, which facilitates the uptake of glucose from the bloodstream. This response helps lower blood glucose levels. Additionally, Metformin decreases the production of glucose by the liver (hepatic glucose production), which is particularly important in type 2 diabetes where the liver may release excess glucose even when blood sugar levels are already elevated. Together, these actions make Metformin an essential medication in the treatment of type 2 diabetes, helping to achieve better glycemic control while reducing the risk of complications associated with diabetes.

Metformin's primary action in managing type 2 diabetes is to improve insulin sensitivity and decrease hepatic glucose production. This dual mechanism is crucial for controlling blood glucose levels in patients with type 2 diabetes.

By enhancing insulin sensitivity, Metformin allows the body's cells to use insulin more effectively, which facilitates the uptake of glucose from the bloodstream. This response helps lower blood glucose levels. Additionally, Metformin decreases the production of glucose by the liver (hepatic glucose production), which is particularly important in type 2 diabetes where the liver may release excess glucose even when blood sugar levels are already elevated.

Together, these actions make Metformin an essential medication in the treatment of type 2 diabetes, helping to achieve better glycemic control while reducing the risk of complications associated with diabetes.