What is the A1C goal recommended by AACE/ACE for most nonpregnant adults?

The A1C goal recommended by the American Association of Clinical Endocrinologists (AACE) and the American College of Endocrinology (ACE) for most nonpregnant adults is set at less than or equal to 6.5%. This goal is based on the understanding that achieving tighter glycemic control can reduce the risk of diabetes-related complications over time. The 6.5% threshold is reflective of a careful balance between effectively managing blood glucose levels and minimizing the risks of hypoglycemia and other treatment burdens, especially in patients who are at higher risk for such complications.

Establishing an A1C target of 6.5% is particularly relevant for adults who are otherwise healthy and can tolerate the potential risks associated with intensive therapy. This goal allows for a more comprehensive approach to diabetes management that considers individual patient factors such as age, comorbid conditions, and diabetes duration, as well as overall treatment goals. Therefore, aligning the A1C goal with this recommendation supports patient-centered care emphasizing personalized treatment strategies.